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Percutaneous Electrical Nerve Stimulation (PENS)

A recently developed deep tissue percutaneous neuromodulation pain therapy device, Deepwave (Biowave Corp, Norwalk, Conn), is a viable alternative for narrowing the analgesic gap in treating osteoarthritic pain. Unlike transcutaneous electrical nerve stimulation, the Deepwave device can deliver a precise electrical signal to a specific volume of tissue in the body that blocks the transmission of pain impulses. The electrical signal created in the body is theorized to have a secondary effect of releasing endorphins and serotonin, and therefore leading to a localized analgesia at the treatment site. This analgesic effect depends on the duration and amplitude of treatment.

Percutaneous Electrical Nerve Stimulation (PENS)

(PENS)PAIN BLOCKING

A recently developed deep tissue percutaneous neuromodulation pain therapy device, Deepwave (Biowave Corp, Norwalk, Conn), is a viable alternative for narrowing the analgesic gap in treating osteoarthritic pain. Unlike transcutaneous electrical nerve stimulation, the Deepwave device can deliver a precise electrical signal to a specific volume of tissue in the body that blocks the transmission of pain impulses. The electrical signal created in the body is theorized to have a secondary effect of releasing endorphins and serotonin, and therefore leading to a localized analgesia at the treatment site. This analgesic effect depends on the duration and amplitude of treatment.

Figure 1: Deepwave (Biowave Corporation, Norwalk, Conn) mechanism of action via frequency conduction block. Normal propagation of pain signal along pain fibers (C-fibers) (A). Deepwave electric field interrupts sodium/potassium ion exchange, thereby inhibiting the cell wall from changing polarity and impeding transmission of pain impulses (B).

The Deepwave device sends a premixed modulated envelope of two high frequency electronic wave forms (“feed signals”) into deep tissue via a larger feed electrode and a smaller pain site electrode called a percutaneous electrode array. The percutaneous electrode array facilitates delivery of the feed signals into deep tissue by providing a direct conductive pathway for current through the outermost layers of skin.

Percutaneous electrode arrays are comprised of 1014 microneedles, each of which is 0.73 mm in length and housed within a 2.5-inch diameter hydrogel-based electrode. Polarized structures in the body cause an electric field to form with a low frequency component equal to the difference in frequency between the two feed signals. Formation of the low frequency field occurs in the…

Published Papers:

Prospective Randomized Single-blinded Controlled Clinical Trial of Percutaneous Neuromodulation Pain Therapy Device Versus Sham for the Osteoarthritic Knee: A Pilot Study

A Randomized Placebo-Controlled Study To Determine Safety and Efficacy In Terms Of Pain Reduction, Increased Range Of Motion, And Reduced Pain Medications, For A Novel Percutaneous Neuromodulation Pain Therapy Device (“Biowave PENS ”) Following Post-Operative Treatments For Total Knee Replacement Procedures

Long Term Use of BiowaveHOME High Frequency Neurostimulation for the Treatment of Chronic Pain in Veterans Following Successful BiowavePRO Neurostim-ulation Therapy in Veterans Administration Hospitals.

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